CA10

Across TCGA patient cohorts, CA10 protein abundance is significantly associated with the RNA expression of many other genes, with 1,547 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CA10-associated genes across cancer lineages are POLR2F, SOX10, and SEPTIN3. Each is linked with CA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both CA10-to-partner and partner-to-CA10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA10 versus POLR2F in GBM, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA10→partner) and Y-score (partner→CA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	POLR2F →	+0.670	+0.802	.002	<.001	3	1
GBM	SOX10 →	+1.905	+0.751	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.348	+0.926	.001	.001	3	1
GBM	NEFH →	+1.128	+0.823	<.001	<.001	3	1
GBM	SYNGR1 →	+0.888	+0.741	<.001	<.001	3	1
GBM	PNPLA5 →	+0.256	+0.713	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,547 associations by consensus.

CA10 vs POLR2F — GBM

Explore this scatter interactively →