CA1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,053 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CA1-associated proteins across cancer lineages are CA13, PIGR_S673, and SH3BGRL2. Each is linked with CA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CA1-to-partner and partner-to-CA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA1 versus CA13 in LUAD, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CA1→partner) and Y-score (partner→CA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADCA13 →+0.701+1.036<.001<.00137
HNSCPIGR_S673 →+1.173+0.682.009.00434
HNSCSH3BGRL2 →+0.477+0.627<.001<.00134
LUADBPNT1 →+0.285+1.036<.001<.00134
HNSCDDAH1 →+0.566+0.667<.001<.00134
LUADEIF4B_S93 →-0.559-0.841<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,053 associations by consensus.

CA1 vs CA13 — LUAD

Per-sample scatter of CA1 vs CA13 in LUAD (Pearson r = 0.69).

Explore this scatter interactively →

Exploration