CA1

Across TCGA patient cohorts, CA1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,379 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CA1-associated genes across cancer lineages are PNPLA3, RASD1, and ZBTB16. Each is linked with CA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CA1-to-partner and partner-to-CA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA1 versus PNPLA3 in LUAD, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA1→partner) and Y-score (partner→CA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PNPLA3 →	-1.101	-0.724	.005	.006	3	1
LUAD	RASD1 →	+1.631	+0.643	.005	.004	3	1
LUAD	ZBTB16 →	+1.678	+0.596	.005	.009	3	1
LUAD	TFCP2L1 →	+1.360	+0.609	.005	.007	3	1
LUAD	SLC2A1 →	-1.987	-1.003	.005	.003	3	1
LUAD	TNFSF4 →	-1.007	-0.927	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,379 associations by consensus.

CA1 vs PNPLA3 — LUAD

Explore this scatter interactively →