C9orf85

Across TCGA pan-cancer cohorts, C9orf85 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C9orf85 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher C9orf85 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated C9orf85 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where C9orf85 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.808	1.000	.003	10	view →
CCRCC	DFS	Median	All	0.868	0.652	.024	8	view →
LUAD	DFS	Median	II,III,IV	0.755	0.991	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C9orf85–UCEC (DFS)

Open the UCEC breakdown →