C9orf78

Across TCGA patient cohorts, C9orf78 protein abundance is significantly associated with the RNA expression of many other genes, with 13,026 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C9orf78-associated genes across cancer lineages are AUNIP, ZNF367, and REXO4. Each is linked with C9orf78 in more than 8 cancer types. Because this analysis shows association rather than direction, both C9orf78-to-partner and partner-to-C9orf78 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf78 versus AUNIP in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf78→partner) and Y-score (partner→C9orf78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AUNIP →	+0.827	+0.178	<.001	.008	3	9
BRCA	ZNF367 →	+1.175	+0.361	<.001	<.001	3	9
OV	REXO4 →	+0.753	+0.441	<.001	<.001	3	9
LSCC	STRBP →	+0.745	+0.209	<.001	<.001	3	9
HNSC	SET →	+0.996	+0.285	<.001	<.001	3	8
LSCC	SMC2 →	+0.766	+0.228	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,026 associations by consensus.

C9orf78 vs AUNIP — UCEC

Explore this scatter interactively →