C9orf78

Across TCGA cell cohorts, C9orf78 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,904 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C9orf78-associated GO terms across cancer lineages are CTP salvage, Spliceosomal tri-snRNP complex assembly, and Transcription pausing by RNA polymerase II. Each is linked with C9orf78 in more than 16 cancer types. Because this analysis shows association rather than direction, both C9orf78-to-partner and partner-to-C9orf78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTP salvage grouped by C9orf78-low versus C9orf78-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf78→partner) and Y-score (partner→C9orf78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CTP salvage →	+0.158	+0.895	.002	.006	3	17
STOMACH	Spliceosomal tri-snRNP complex assembly →	+0.122	+0.872	.005	.001	3	14
BONE	Transcription pausing by RNA polymerase II →	+0.134	+0.621	.002	<.001	3	14
BLOOD_Lymphoma	RNA export from nucleus →	+0.089	+0.874	<.001	<.001	3	14
PANCREAS	Dolichol phosphate mannose biosynthetic process →	+0.106	+0.764	.001	.006	3	13
UPPER_AERODIGESTIVE_TRACT	Spliceosomal snRNP assembly →	+0.082	+0.674	.004	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,904 associations by consensus.

CTP salvage by C9orf78 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →