C9orf64

Across TCGA pan-cancer cohorts, C9orf64 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C9orf64 data layer compared with 27 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher C9orf64 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C9orf64 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

KICH, LIHC, and LUSC are the cancer types where C9orf64 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
LIHC	OS	Median	All	0.226	0.773	.008	9	view →
LUSC	OS	Median	II,III,IV	0.170	0.629	.041	3	view →
SKCM	OS	Median	All	0.743	0.332	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

C9orf64–KICH (DFS)

Open the KICH breakdown →