C9orf64

Across TCGA patient cohorts, C9orf64 protein abundance is significantly associated with the RNA expression of many other genes, with 13,550 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C9orf64-associated genes across cancer lineages are ALG2, TSC1, and CDK20. Each is linked with C9orf64 in more than 7 cancer types. Because this analysis shows association rather than direction, both C9orf64-to-partner and partner-to-C9orf64 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf64 versus ALG2 in HNSC, with a Pearson correlation of 0.16.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf64→partner) and Y-score (partner→C9orf64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ALG2 →	+0.435	+0.200	<.001	.001	2	8
HNSC	TSC1 →	+0.470	+0.258	<.001	<.001	3	6
UCEC	CDK20 →	+0.702	+0.227	.001	<.001	3	5
OV	SPIN1 →	+0.632	+0.287	.006	.009	2	6
BRCA	RBM18 →	+0.740	+0.516	<.001	<.001	3	5
HNSC	ZNF484 →	+0.565	+0.314	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,550 associations by consensus.

C9orf64 vs ALG2 — HNSC

Explore this scatter interactively →