C9orf64

Across TCGA cell cohorts, C9orf64 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,029 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C9orf64-associated GO terms across cancer lineages are Response to type I interferon, Response to norepinephrine, and Cellular response to norepinephrine stimulus. Each is linked with C9orf64 in more than 5 cancer types. Because this analysis shows association rather than direction, both C9orf64-to-partner and partner-to-C9orf64 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to type I interferon grouped by C9orf64-low versus C9orf64-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf64→partner) and Y-score (partner→C9orf64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Response to type I interferon →	+0.087	+1.298	.001	.002	3	6
BONE	Response to norepinephrine →	-0.159	-2.065	.007	.002	3	5
BONE	Cellular response to norepinephrine stimulus →	-0.159	-2.065	.007	.002	3	5
BONE	Negative regulation of collagen metabolic process →	+0.161	+1.483	<.001	.004	3	5
BONE	Mesodermal cell fate commitment →	+1.167	+1.990	<.001	<.001	3	5
BLOOD_Lymphoma	Response to arsenic-containing substance →	+0.084	+1.655	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,029 associations by consensus.

Response to type I interferon by C9orf64 expression — BLOOD_Lymphoma

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