C9orf47

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C9orf47 mutation is significantly associated with the RNA expression of many other genes, with 3,204 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C9orf47-associated genes across cancer lineages are OR10D4P, UHRF1, and UVSSA. Each is linked with C9orf47 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf47-to-partner and partner-to-C9orf47 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf47→partner) and Y-score (partner→C9orf47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCOR10D4P →+0.025+4.020<.001.00932
UCECUHRF1 →+1.009+2.332<.001<.00132
UCECUVSSA →+0.428+2.321.001.00132
UCECVPS39 →+0.428+3.743<.001<.00132
UCECCCNDBP1 →+0.560+3.648<.001.00132
UCECGOLGA2 →+0.482+2.550<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,204 associations by consensus.

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