C9orf40

Across TCGA patient cohorts, C9orf40 protein abundance is significantly associated with the RNA expression of many other genes, with 5,798 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C9orf40-associated genes across cancer lineages are HEMGN, HBB, and ALAS2. Each is linked with C9orf40 in more than 3 cancer types. Because this analysis shows association rather than direction, both C9orf40-to-partner and partner-to-C9orf40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf40 versus HEMGN in GBM, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf40→partner) and Y-score (partner→C9orf40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HEMGN →	+0.520	+0.642	<.001	<.001	3	4
GBM	HBB →	+1.617	+0.412	<.001	<.001	3	4
CCRCC	ALAS2 →	+0.870	+0.359	.001	.003	2	4
GBM	HBA1 →	+1.597	+0.473	<.001	<.001	3	3
CCRCC	SLC4A1 →	+0.678	+0.463	.005	<.001	3	3
HNSC	TRPM6 →	+0.555	+0.303	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,798 associations by consensus.

C9orf40 vs HEMGN — GBM

Explore this scatter interactively →