C9orf40

Across TCGA cell cohorts, C9orf40 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,529 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C9orf40-associated GO terms across cancer lineages are Positive regulation of cell cycle process, Positive regulation of cell cycle, and Positive regulation of chromosome segregation. Each is linked with C9orf40 in more than 15 cancer types. Because this analysis shows association rather than direction, both C9orf40-to-partner and partner-to-C9orf40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle process grouped by C9orf40-low versus C9orf40-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf40→partner) and Y-score (partner→C9orf40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of cell cycle process →	+0.068	+1.060	<.001	<.001	3	16
KIDNEY	Positive regulation of cell cycle →	+0.062	+1.005	<.001	<.001	3	15
KIDNEY	Positive regulation of chromosome segregation →	+0.141	+1.161	<.001	<.001	3	15
KIDNEY	Cell cycle checkpoint signaling →	+0.058	+1.035	.001	<.001	3	15
BLOOD_Lymphoma	Regulation of chromosome segregation →	+0.105	+0.887	<.001	<.001	3	15
KIDNEY	Regulation of mitotic nuclear division →	+0.104	+0.904	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,529 associations by consensus.

Positive regulation of cell cycle process by C9orf40 expression — OVARY

Explore this box plot interactively →