Across TCGA patient cohorts, C9orf153 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C9orf153-associated genes across cancer lineages are Astrocytes, CMP, and lymphatic Endothelial cells. Each is linked with C9orf153 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf153-to-partner and partner-to-C9orf153 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf153→partner) and Y-score (partner→C9orf153) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Astrocytes →	+0.106	+3.825	<.001	.041	3	1
UCEC	CMP →	-0.032	-3.000	.022	.036	3	1
UCEC	lymphatic Endothelial cells →	-0.023	-3.281	.037	.010	3	1
UCEC	Sebocytes →	-0.024	-3.137	.035	.019	3	1
UCEC	Neurons →	-0.021	-2.563	.016	.011	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

C9orf153 survival (RNA) · tumor vs normal (RNA) · all C9orf153 data types