Across TCGA patient cohorts, C9orf152 protein abundance is significantly associated with the RNA expression of many other genes, with 4,872 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C9orf152-associated genes across cancer lineages are CDC25B, COBL, and NPDC1. Each is linked with C9orf152 in more than 2 cancer types. Because this analysis shows association rather than direction, both C9orf152-to-partner and partner-to-C9orf152 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf152→partner) and Y-score (partner→C9orf152) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDC25B →	-1.207	-0.945	.002	.007	3	3
UCEC	COBL →	+1.461	+1.036	<.001	<.001	3	3
BRCA	NPDC1 →	+2.114	+1.345	<.001	<.001	3	3
BRCA	MANSC1 →	+1.309	+1.266	<.001	<.001	3	3
BRCA	CDCA3 →	-1.165	-1.130	.002	.001	3	3
BRCA	E2F3 →	-0.812	-0.940	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,872 associations by consensus.

Exploration

C9orf152 survival (RNA) · tumor vs normal (RNA) · all C9orf152 data types