Across TCGA cell cohorts, C9orf135 RNA expression is significantly associated with the go_rna of many other GO terms, with 691 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible C9orf135-associated GO terms across cancer lineages are Tail-anchored membrane protein insertion into ER membrane, Protein insertion into ER membrane, and Sodium ion import across plasma membrane. Each is linked with C9orf135 in more than 5 cancer types. Because this analysis shows association rather than direction, both C9orf135-to-partner and partner-to-C9orf135 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf135→partner) and Y-score (partner→C9orf135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Tail-anchored membrane protein insertion into ER membrane →	+0.060	+0.052	.003	.003	3	6
LUNG_SCLC	Protein insertion into ER membrane →	+0.078	+1.503	.003	.009	2	5
CNS	Sodium ion import across plasma membrane →	-0.043	-0.172	<.001	<.001	3	4
CNS	Endoplasmic reticulum tubular network membrane organization →	-0.092	-0.208	.001	.002	3	4
LUNG_SCLC	Positive regulation of epithelial cell differentiation →	+0.129	+1.926	<.001	<.001	3	4
LUNG_SCLC	Specification of symmetry →	-0.050	-1.138	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 691 associations by consensus.

Exploration

C9orf135 survival (RNA) · tumor vs normal (RNA) · all C9orf135 data types