C9orf131

Across TCGA patient cohorts, C9orf131 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,930 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible C9orf131-associated proteins across cancer lineages are VPS13D_S2671, EEA1_S52, and SLK_S348. Each is linked with C9orf131 in more than 4 cancer types. Because this analysis shows association rather than direction, both C9orf131-to-partner and partner-to-C9orf131 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf131 versus VPS13D_S2671 in HNSC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf131→partner) and Y-score (partner→C9orf131) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VPS13D_S2671 →	-0.848	-0.592	<.001	<.001	3	5
CCRCC	EEA1_S52 →	-0.854	-0.548	<.001	<.001	3	4
LSCC	SLK_S348 →	-0.985	-0.552	.005	.004	3	4
LSCC	HINT2 →	+0.509	+0.529	<.001	<.001	3	4
PDAC	VCP →	+0.325	+0.594	<.001	<.001	3	4
GBM	USP9X_S1609 →	-0.399	-0.446	.006	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,930 associations by consensus.

C9orf131 vs VPS13D_S2671 — HNSC

Explore this scatter interactively →