C9orf131

Across TCGA patient cohorts, C9orf131 mutation is significantly associated with the RNA expression of many other genes, with 2,980 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C9orf131-associated genes across cancer lineages are RNA5SP162, EME1, and LRR1. Each is linked with C9orf131 in more than 2 cancer types. Because this analysis shows association rather than direction, both C9orf131-to-partner and partner-to-C9orf131 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP162 grouped by C9orf131-low versus C9orf131-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf131→partner) and Y-score (partner→C9orf131) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP162 →	+0.314	+3.473	<.001	.004	3	3
UCEC	EME1 →	+0.645	+2.765	<.001	<.001	3	3
UCEC	LRR1 →	+0.529	+2.828	<.001	.001	3	3
UCEC	CKAP2L →	+0.495	+2.439	.007	.001	3	3
UCEC	RRM2 →	+0.797	+2.058	<.001	<.001	3	3
UCEC	UBE2T →	+0.554	+1.820	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,980 associations by consensus.

RNA5SP162 by C9orf131 expression — LUAD

Explore this box plot interactively →