C9orf116

Across TCGA pan-cancer cohorts, C9orf116 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C9orf116 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C9orf116 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated C9orf116 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD are the cancer types where C9orf116 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.874	0.348	.033	3	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

C9orf116–LUAD (OS)

Open the LUAD breakdown →