C9orf116

Across TCGA patient cohorts, C9orf116 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,676 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C9orf116-associated proteins across cancer lineages are WDR54, IFT43, and TTC25_S542. Each is linked with C9orf116 in more than 6 cancer types. Because this analysis shows association rather than direction, both C9orf116-to-partner and partner-to-C9orf116 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf116 versus WDR54 in BRCA, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf116→partner) and Y-score (partner→C9orf116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WDR54 →	+0.504	+1.022	<.001	<.001	3	7
HNSC	IFT43 →	+0.701	+0.738	<.001	.006	3	7
UCEC	TTC25_S542 →	+1.456	+1.562	<.001	<.001	3	6
BRCA	CETN2 →	+0.406	+0.859	<.001	<.001	3	6
UCEC	DPCD →	+0.485	+1.030	<.001	<.001	3	6
BRCA	OSCP1 →	+0.721	+1.363	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,676 associations by consensus.

C9orf116 vs WDR54 — BRCA

Explore this scatter interactively →