C9orf116

Across TCGA patient cohorts, C9orf116 protein abundance is significantly associated with the RNA expression of many other genes, with 944 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C9orf116-associated genes across cancer lineages are KCNA1, RSPH4A, and ARMC2. Each is linked with C9orf116 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf116-to-partner and partner-to-C9orf116 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf116 versus KCNA1 in LSCC, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf116→partner) and Y-score (partner→C9orf116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KCNA1 →	+0.268	+1.809	<.001	.007	3	2
LSCC	RSPH4A →	+2.043	+1.845	.001	.001	3	2
LSCC	ARMC2 →	+0.719	+1.555	.001	.005	3	2
LSCC	C20orf85 →	+3.512	+1.655	<.001	.007	3	2
LSCC	DSTN →	+0.764	+1.602	.003	.008	3	2
LSCC	CACNG6 →	+1.553	+2.075	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 944 associations by consensus.

C9orf116 vs KCNA1 — LSCC

Explore this scatter interactively →