C8orf89

Across TCGA patient cohorts, C8orf89 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C8orf89-associated genes across cancer lineages are MIR4682, RNA5SP124, and RNA5-8SP7. Each is linked with C8orf89 in more than 1 cancer types. Because this analysis shows association rather than direction, both C8orf89-to-partner and partner-to-C8orf89 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4682 grouped by C8orf89-low versus C8orf89-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf89→partner) and Y-score (partner→C8orf89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4682 →	+0.585	+3.204	.001	.006	3	1
UCEC	RNA5SP124 →	+0.774	+3.903	<.001	<.001	3	1
UCEC	RNA5-8SP7 →	+0.232	+4.132	.002	.009	3	1
UCEC	RNA5SP128 →	+0.496	+3.567	<.001	.005	3	1
UCEC	MIR517C →	+0.347	+4.400	<.001	.006	3	1
UCEC	RNU6-1242P →	+0.416	+3.344	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

MIR4682 by C8orf89 expression — UCEC

Explore this box plot interactively →