C8orf89

Across TCGA cell cohorts, C8orf89 RNA expression is significantly associated with the go_rna of many other GO terms, with 530 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C8orf89-associated GO terms across cancer lineages are Positive regulation of T cell activation, L-histidine transmembrane transport, and Positive regulation of leukocyte cell-cell adhesion. Each is linked with C8orf89 in more than 4 cancer types. Because this analysis shows association rather than direction, both C8orf89-to-partner and partner-to-C8orf89 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of T cell activation grouped by C8orf89-low versus C8orf89-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf89→partner) and Y-score (partner→C8orf89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of T cell activation →	+0.072	+0.200	<.001	.004	3	5
LUNG_SCLC	L-histidine transmembrane transport →	+0.128	+0.030	.006	.007	3	4
BONE	Positive regulation of leukocyte cell-cell adhesion →	+0.057	+0.157	<.001	.006	3	4
SOFT_TISSUE	Presynaptic modulation of chemical synaptic transmission →	-0.055	-0.146	.008	.008	3	3
LIVER	Regulation of epithelial to mesenchymal transition →	+0.108	+0.056	.003	.008	3	3
BLOOD_Lymphoma	Lung cell differentiation →	+0.181	+0.239	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 530 associations by consensus.

Positive regulation of T cell activation by C8orf89 expression — BONE

Explore this box plot interactively →