C8orf88

Across TCGA pan-cancer cohorts, C8orf88 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C8orf88 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher C8orf88 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C8orf88 expression acts as an unfavorable survival marker.

UCEC and SCLC are the cancer types where C8orf88 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.231	0.873	<.001	36	view →
SCLC	OS	Median	All	0.219	0.650	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

C8orf88–UCEC (OS)

Open the UCEC breakdown →