Across TCGA pan-cancer cohorts, C8orf82 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C8orf82 data layer compared with 22 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher C8orf82 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C8orf82 expression acts as an unfavorable survival marker.

UCEC, MESO, and LIHC are the cancer types where C8orf82 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.061	0.588	.018	12	view →
MESO	DFS	Median	III,IV	0.078	0.376	.012	9	view →
LIHC	OS	Median	All	0.144	0.688	.013	9	view →
SKCM	OS	Median	All	0.477	0.787	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: C8orf82 tumor-vs-normal RNA expression · all C8orf82 data types