Across TCGA pan-cancer cohorts, C8orf82 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated C8orf82 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher C8orf82 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated C8orf82 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

UCEC, PDAC, and LSCC are the cancer types where C8orf82 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.936	1.000	.022	8	view →
PDAC	OS	Median	II,III,IV	0.435	0.288	.020	6	view →
LSCC	DFS	Median	All	0.453	0.868	.020	4	view →
CCRCC	DFS	Tertile	III,IV	0.423	0.753	.026	3	view →
HNSC	OS	Tertile	II,III,IV	0.924	1.000	.018	3	view →
LUAD	OS	Median	III,IV	0.634	0.212	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: C8orf82 tumor-vs-normal RNA expression · all C8orf82 data types