Across TCGA pan-cancer cohorts, C8orf76 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C8orf76 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher C8orf76 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C8orf76 expression acts as an unfavorable survival marker.

SCLC, LIHC, and SARC are the cancer types where C8orf76 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Median	All	0.164	0.625	.018	12	view →
LIHC	DFS	Median	All	0.100	0.544	.002	12	view →
SARC	OS	Median	All	0.174	0.745	.005	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: C8orf76 tumor-vs-normal RNA expression · all C8orf76 data types