Across TCGA patient cohorts, C8orf76 protein abundance is significantly associated with the RNA expression of many other genes, with 1,194 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C8orf76-associated genes across cancer lineages are MCAT, PLEKHA1, and DOHH. Each is linked with C8orf76 in more than 2 cancer types. Because this analysis shows association rather than direction, both C8orf76-to-partner and partner-to-C8orf76 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf76→partner) and Y-score (partner→C8orf76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MCAT →	+0.711	+0.533	.002	.002	3	2
BRCA	PLEKHA1 →	-0.971	-0.521	.006	.003	3	2
BRCA	DOHH →	+1.268	+0.702	.003	.003	3	2
BRCA	LSM4 →	+1.431	+0.701	<.001	.004	3	2
LUAD	PAPPA →	-1.424	-0.421	<.001	.004	3	2
LSCC	PDAP1 →	+0.749	+0.568	<.001	.003	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,194 associations by consensus.

Exploration

C8orf76 survival (RNA) · tumor vs normal (RNA) · all C8orf76 data types