Across TCGA patient cohorts, C8orf76 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C8orf76-associated genes across cancer lineages are CICP1, MIR3136, and OR2AM1P. Each is linked with C8orf76 in more than 1 cancer types. Because this analysis shows association rather than direction, both C8orf76-to-partner and partner-to-C8orf76 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf76→partner) and Y-score (partner→C8orf76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CICP1 →	+0.013	+4.884	<.001	.004	3	2
SKCM	MIR3136 →	+0.589	+3.801	.002	.009	3	2
SKCM	OR2AM1P →	+0.202	+4.884	<.001	.004	3	1
SKCM	ZNF863P →	+0.169	+4.208	<.001	.003	3	1
SKCM	MTCO3P41 →	+0.111	+4.495	<.001	.007	3	1
SKCM	RN7SL254P →	+0.098	+4.385	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

C8orf76 survival (RNA) · tumor vs normal (RNA) · all C8orf76 data types