C8orf44

Across TCGA patient cohorts, C8orf44 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,013 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C8orf44-associated proteins across cancer lineages are CXXC1, RAD21, and WDR5. Each is linked with C8orf44 in more than 5 cancer types. Because this analysis shows association rather than direction, both C8orf44-to-partner and partner-to-C8orf44 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C8orf44 versus CXXC1 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf44→partner) and Y-score (partner→C8orf44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CXXC1 →	+0.334	+0.503	<.001	<.001	3	6
GBM	RAD21 →	+0.261	+0.317	.001	.008	3	6
LSCC	WDR5 →	+0.251	+0.445	.001	.004	3	6
BRCA	TRADD →	-0.336	-0.594	<.001	<.001	3	5
BRCA	NCOA2_S29 →	+0.495	+0.597	.001	<.001	3	5
LSCC	NELFCD →	+0.258	+0.526	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,013 associations by consensus.

C8orf44 vs CXXC1 — GBM

Explore this scatter interactively →