C8orf44

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C8orf44 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C8orf44-associated genes across cancer lineages are DEFB129. Each is linked with C8orf44 in more than 1 cancer types. Because this analysis shows association rather than direction, both C8orf44-to-partner and partner-to-C8orf44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB129 grouped by C8orf44-low versus C8orf44-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf44→partner) and Y-score (partner→C8orf44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaDEFB129 →+0.064+5.201<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

DEFB129 by C8orf44 expression — BLOOD_Leukemia

Box plot of DEFB129 in C8orf44-low vs C8orf44-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration