C8orf37

Across TCGA pan-cancer cohorts, C8orf37 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C8orf37 data layer compared with 21 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher C8orf37 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C8orf37 expression acts as an unfavorable survival marker.

KIRC, LUAD, and SKCM are the cancer types where C8orf37 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.181	0.805	.002	21	view →
LUAD	OS	Median	All	0.236	0.788	.006	9	view →
SKCM	OS	Median	All	0.111	0.323	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C8orf37–KIRC (OS)

Open the KIRC breakdown →