C8orf37

Across TCGA cell cohorts, C8orf37 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C8orf37-associated genes across cancer lineages are INSL5, OR10W1, and OR4F5. Each is linked with C8orf37 in more than 1 cancer types. Because this analysis shows association rather than direction, both C8orf37-to-partner and partner-to-C8orf37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INSL5 grouped by C8orf37-low versus C8orf37-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf37→partner) and Y-score (partner→C8orf37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	INSL5 →	+0.385	+3.626	<.001	.006	3	1
LARGE_INTESTINE	OR10W1 →	+0.016	+3.977	<.001	.001	3	1
LARGE_INTESTINE	OR4F5 →	+0.024	+3.345	<.001	.007	3	1
LARGE_INTESTINE	MAGEB1 →	+0.193	+3.878	<.001	.003	3	1
LUNG_NSCLC_LUAD	TPSB2 →	+0.094	+3.821	.001	.007	3	1
LUNG_NSCLC_LUAD	USP17L15 →	+0.009	+4.228	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

INSL5 by C8orf37 expression — LARGE_INTESTINE

Explore this box plot interactively →