C8orf37-AS1

Across TCGA pan-cancer cohorts, C8orf37-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of C8orf37-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where C8orf37-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C8orf37-AS1 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

COAD, KICH, and LUSC are the cancer types where C8orf37-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C8orf37-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.219	<.001	11	view →
KICH	All	III,IV	−0.692	<.001	10	view →
LUSC	All	II,III,IV	−0.425	<.001	6	view →
BRCA	Female	All	+0.333	<.001	6	view →
LIHC	Male	All	+0.233	<.001	5	view →
THCA	Male	All	−0.308	<.001	4	view →
CHOL	Male	All	+0.235	.002	4	view →
STAD	All	All	+0.231	.002	3	view →
READ	Female	All	+0.320	.023	2	view →
PAAD	Male	All	−0.255	.009	2	view →
HNSC	Male	II,III,IV	−0.089	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

C8orf37-AS1–COAD

Open the COAD breakdown →