C8orf31

Across TCGA patient cohorts, C8orf31 mutation is significantly associated with the RNA expression of many other genes, with 164 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C8orf31-associated genes across cancer lineages are RNA5SP285, RNU6-1213P, and MRPS18BP1. Each is linked with C8orf31 in more than 1 cancer types. Because this analysis shows association rather than direction, both C8orf31-to-partner and partner-to-C8orf31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP285 grouped by C8orf31-low versus C8orf31-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf31→partner) and Y-score (partner→C8orf31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP285 →	+0.386	+3.694	<.001	.003	3	2
LUAD	RNU6-1213P →	+0.508	+7.930	<.001	.008	3	2
BRCA	MRPS18BP1 →	+0.268	+4.527	<.001	.007	3	2
BRCA	VTI1BP4 →	+0.165	+4.065	.007	.005	3	2
SKCM	RN7SKP228 →	+0.136	+3.970	<.001	.001	3	2
BLCA	MIR1225 →	+0.468	+7.640	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 164 associations by consensus.

RNA5SP285 by C8orf31 expression — UCEC

Explore this box plot interactively →