C8G

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C8G mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C8G-associated genes across cancer lineages are Myosin-IIa_pS1943. Each is linked with C8G in more than 1 cancer types. Because this analysis shows association rather than direction, both C8G-to-partner and partner-to-C8G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa_pS1943 grouped by C8G-low versus C8G-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8G→partner) and Y-score (partner→C8G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMyosin-IIa_pS1943 →+0.264+2.820.037.03631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Myosin-IIa_pS1943 by C8G expression — UCEC

Box plot of Myosin-IIa_pS1943 in C8G-low vs C8G-high samples in UCEC.

Explore this box plot interactively →

Exploration