C8G

Across TCGA cell cohorts, C8G RNA expression is significantly associated with the go_rna of many other GO terms, with 3,117 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C8G-associated GO terms across cancer lineages are Fatty acid catabolic process, Fatty acid beta-oxidation, and Intracellular sphingolipid homeostasis. Each is linked with C8G in more than 12 cancer types. Because this analysis shows association rather than direction, both C8G-to-partner and partner-to-C8G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid catabolic process grouped by C8G-low versus C8G-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C8G→partner) and Y-score (partner→C8G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Fatty acid catabolic process →	+0.081	+0.654	<.001	<.001	2	13
LUNG_NSCLC_LUSC	Fatty acid beta-oxidation →	+0.073	+0.388	.007	.008	1	12
OESOPHAGUS	Intracellular sphingolipid homeostasis →	+0.202	+1.026	<.001	<.001	3	9
BREAST	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.141	+0.587	.002	.005	3	9
SOFT_TISSUE	Vesicle uncoating →	+0.135	+0.439	.001	.001	3	8
OESOPHAGUS	Negative regulation of response to endoplasmic reticulum stress →	+0.139	+1.271	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,117 associations by consensus.

Fatty acid catabolic process by C8G expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →