C7orf69

Across TCGA pan-cancer cohorts, C7orf69 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C7orf69 data layer compared with 17 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C7orf69 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated C7orf69 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where C7orf69 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.526	0.790	.002	26	view →
CCRCC	OS	Median	III,IV	0.535	0.876	.005	14	view →
LUAD	DFS	Median	II,III,IV	1.000	0.754	.022	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C7orf69–HNSC (DFS)

Open the HNSC breakdown →