C6orf89

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C6orf89 mutation is significantly associated with the RNA expression of many other genes, with 1,089 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf89-associated genes across cancer lineages are MIR4510, LINC02297, and ATP5F1AP7. Each is linked with C6orf89 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf89-to-partner and partner-to-C6orf89 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf89→partner) and Y-score (partner→C6orf89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PRADMIR4510 →+0.348+7.939<.001.00832
SKCMLINC02297 →+0.133+4.947<.001<.00132
READATP5F1AP7 →+0.094+5.421<.001.00532
READEEF1E1-BLOC1S5 →+0.204+5.219<.001.00632
READOR10B1P →+0.084+5.653<.001.00332
BRCAOR56A5 →+0.174+4.220<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,089 associations by consensus.

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