Across TCGA patient cohorts, C6orf89 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf89-associated genes across cancer lineages are INPP4B, mTOR_pS2448, and eIF4G. Each is linked with C6orf89 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf89-to-partner and partner-to-C6orf89 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf89→partner) and Y-score (partner→C6orf89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.382	-2.321	.018	.034	3	2
UCEC	mTOR_pS2448 →	-0.205	-2.980	.006	.036	3	2
UCEC	eIF4G →	+0.363	+2.321	.019	.035	3	1
UCEC	Gab2 →	+0.353	+2.321	.049	.035	3	1
UCEC	Ku80 →	+0.282	+2.335	.017	.020	3	1
UCEC	Notch1 →	+0.209	+3.009	.003	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

C6orf89 survival (RNA) · tumor vs normal (RNA) · all C6orf89 data types