Across TCGA cell cohorts, C6orf89 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C6orf89-associated genes across cancer lineages are OR5H2, SCYGR2, and TRIM42. Each is linked with C6orf89 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf89-to-partner and partner-to-C6orf89 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf89→partner) and Y-score (partner→C6orf89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR5H2 →	+0.276	+5.285	<.001	.003	3	1
STOMACH	SCYGR2 →	+0.116	+5.285	<.001	.003	3	1
BLOOD_Leukemia	TRIM42 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR6B3 →	+0.022	+5.539	<.001	.003	3	1
BLOOD_Leukemia	IFNA4 →	+0.024	+4.922	.009	.009	3	1
BLOOD_Leukemia	OR52E5 →	+0.016	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

C6orf89 survival (RNA) · tumor vs normal (RNA) · all C6orf89 data types