Across TCGA patient cohorts, C6orf58 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,122 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible C6orf58-associated GO terms across cancer lineages are Smoothened signaling pathway, Late endosome to vacuole transport, and Protein-containing complex disassembly. Each is linked with C6orf58 in more than 21 cancer types. Because this analysis shows association rather than direction, both C6orf58-to-partner and partner-to-C6orf58 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf58→partner) and Y-score (partner→C6orf58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Smoothened signaling pathway →	+0.037	+0.284	<.001	<.001	3	22
TGCT	Late endosome to vacuole transport →	+0.060	+0.396	<.001	<.001	3	21
THYM	Protein-containing complex disassembly →	+0.031	+0.297	<.001	<.001	3	21
THYM	Negative regulation of IRE1-mediated unfolded protein response →	+0.079	+0.291	<.001	<.001	3	20
UVM	7-methylguanosine RNA capping →	+0.070	+0.224	<.001	<.001	3	20
THYM	Epigenetic regulation of gene expression →	+0.041	+0.313	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,122 associations by consensus.

Exploration

C6orf58 survival (RNA) · tumor vs normal (RNA) · all C6orf58 data types