Across TCGA patient cohorts, C6orf58 mutation is significantly associated with the RNA expression of many other genes, with 1,314 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf58-associated genes across cancer lineages are MTND3P13, MIR8082, and TCP1. Each is linked with C6orf58 in more than 2 cancer types. Because this analysis shows association rather than direction, both C6orf58-to-partner and partner-to-C6orf58 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf58→partner) and Y-score (partner→C6orf58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MTND3P13 →	+0.188	+4.893	<.001	.005	3	3
HNSC	MIR8082 →	+0.216	+4.339	<.001	.007	3	3
SKCM	TCP1 →	+0.533	+3.372	.002	.004	3	3
SKCM	MRPL46 →	+0.355	+3.019	.004	<.001	3	2
UCEC	MRPS11 →	+0.485	+3.212	<.001	.009	3	2
UCEC	NDUFA6 →	+0.611	+3.632	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,314 associations by consensus.

Exploration

C6orf58 survival (RNA) · tumor vs normal (RNA) · all C6orf58 data types