Across TCGA cell cohorts, C6orf58 mutation is significantly associated with the drug of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C6orf58-associated genes across cancer lineages are GSK2801, 50869, and 729189. Each is linked with C6orf58 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf58-to-partner and partner-to-C6orf58 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf58→partner) and Y-score (partner→C6orf58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2801 →	+0.319	+2.649	.045	.046	3	1
LARGE_INTESTINE	50869 →	+0.530	+2.678	.011	.037	2	1
LARGE_INTESTINE	729189 →	+0.302	+2.649	.017	.046	2	1
LARGE_INTESTINE	Nelarabine →	+0.314	+2.649	.016	.046	1	1
LARGE_INTESTINE	123138 →	+0.294	+2.649	.048	.046	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

C6orf58 survival (RNA) · tumor vs normal (RNA) · all C6orf58 data types