C6orf223

Across TCGA cell cohorts, C6orf223 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,033 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C6orf223-associated GO terms across cancer lineages are Negative regulation of myeloid leukocyte mediated immunity, Sulfide oxidation, and Cholesterol biosynthetic process via desmosterol. Each is linked with C6orf223 in more than 7 cancer types. Because this analysis shows association rather than direction, both C6orf223-to-partner and partner-to-C6orf223 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myeloid leukocyte mediated immunity grouped by C6orf223-low versus C6orf223-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf223→partner) and Y-score (partner→C6orf223) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of myeloid leukocyte mediated immunity →	+1.376	+1.522	.001	.005	3	8
LARGE_INTESTINE	Sulfide oxidation →	+0.195	+1.909	<.001	<.001	3	7
LARGE_INTESTINE	Cholesterol biosynthetic process via desmosterol →	+0.166	+1.827	<.001	<.001	3	7
LARGE_INTESTINE	Cholesterol biosynthetic process via lathosterol →	+0.135	+1.813	<.001	<.001	3	7
LARGE_INTESTINE	Sulfide oxidation, using sulfide:quinone oxidoreductase →	+0.195	+1.909	<.001	<.001	3	7
STOMACH	Response to molecule of fungal origin →	+1.698	+1.955	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,033 associations by consensus.

Negative regulation of myeloid leukocyte mediated immunity by C6orf223 expression — LARGE_INTESTINE

Explore this box plot interactively →