C6orf223

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C6orf223 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C6orf223-associated genes across cancer lineages are CFHR2. Each is linked with C6orf223 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf223-to-partner and partner-to-C6orf223 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by C6orf223-low versus C6orf223-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf223→partner) and Y-score (partner→C6orf223) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECFHR2 →+0.057+5.022<.001.00231
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CFHR2 by C6orf223 expression — LARGE_INTESTINE

Box plot of CFHR2 in C6orf223-low vs C6orf223-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration