Across TCGA patient cohorts, C6orf163 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf163-associated genes across cancer lineages are FAM236A, RNA5SP414, and C12orf43. Each is linked with C6orf163 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf163-to-partner and partner-to-C6orf163 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf163→partner) and Y-score (partner→C6orf163) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM236A →	+0.089	+9.057	<.001	.003	3	1
UCEC	RNA5SP414 →	+0.603	+2.670	.001	.009	3	1
UCEC	C12orf43 →	+0.419	+3.202	.003	.009	3	1
UCEC	CLEC12A →	+0.627	+3.255	<.001	.009	3	1
UCEC	TIMM22 →	+0.467	+3.223	.008	.009	3	1
UCEC	MUL1 →	+0.607	+3.201	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Exploration

C6orf163 survival (RNA) · tumor vs normal (RNA) · all C6orf163 data types