Across TCGA pan-cancer cohorts, C6orf120 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C6orf120 data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C6orf120 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated C6orf120 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

LUAD, PDAC, and HNSC are the cancer types where C6orf120 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.768	0.900	.007	20	view →
PDAC	OS	Quartile	All	0.393	0.734	.006	19	view →
HNSC	DFS	Median	II,III,IV	0.989	0.898	.042	3	view →
CCRCC	OS	Median	III,IV	0.865	0.521	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: C6orf120 tumor-vs-normal RNA expression · all C6orf120 data types