Across TCGA patient cohorts, C6orf120 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf120-associated genes across cancer lineages are MEK1, INPP4B, and Ku80. Each is linked with C6orf120 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf120-to-partner and partner-to-C6orf120 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf120→partner) and Y-score (partner→C6orf120) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.505	+3.584	.004	.002	3	2
UCEC	INPP4B →	-0.313	-3.000	.045	.036	2	2
UCEC	Ku80 →	+0.294	+2.472	.010	.011	3	1
UCEC	Notch1 →	+0.233	+3.179	<.001	.010	3	1
UCEC	p62 Lck ligand →	+0.348	+2.459	.026	.020	3	1
UCEC	P-Cadherin →	-0.157	-2.990	.024	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

C6orf120 survival (RNA) · tumor vs normal (RNA) · all C6orf120 data types