C6orf118

Across TCGA patient cohorts, C6orf118 protein abundance is significantly associated with the RNA expression of many other genes, with 4,920 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C6orf118-associated genes across cancer lineages are DPH2, PHC2-AS1, and FAM27E3. Each is linked with C6orf118 in more than 2 cancer types. Because this analysis shows association rather than direction, both C6orf118-to-partner and partner-to-C6orf118 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C6orf118 versus DPH2 in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf118→partner) and Y-score (partner→C6orf118) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DPH2 →	+0.495	+0.775	<.001	.004	3	3
PDAC	PHC2-AS1 →	+1.620	+0.380	<.001	.007	3	3
BRCA	FAM27E3 →	+0.777	+0.647	.001	.001	3	3
COAD	AK2 →	+0.474	+0.626	<.001	.008	3	3
HNSC	MYL2 →	-2.330	-0.520	.002	.004	3	2
HNSC	OTUD7A →	+0.528	+0.508	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,920 associations by consensus.

C6orf118 vs DPH2 — OV

Explore this scatter interactively →