C6orf118

Across TCGA cell cohorts, C6orf118 RNA expression is significantly associated with the go_rna of many other GO terms, with 765 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible C6orf118-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Regulation of DNA repair, and Regulation of DNA recombination. Each is linked with C6orf118 in more than 5 cancer types. Because this analysis shows association rather than direction, both C6orf118-to-partner and partner-to-C6orf118 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by C6orf118-low versus C6orf118-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf118→partner) and Y-score (partner→C6orf118) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.047	+0.536	.001	.003	3	6
SOFT_TISSUE	Regulation of DNA repair →	+0.042	+0.384	.001	.005	3	6
KIDNEY	Regulation of DNA recombination →	+0.030	+0.199	.009	.005	3	6
SOFT_TISSUE	Regulation of double-strand break repair →	+0.049	+0.558	.004	.001	3	6
LUNG_SCLC	Regulation of organelle assembly →	+0.042	+0.883	<.001	<.001	3	6
LUNG_SCLC	Regulation of protein localization to Cajal body →	+0.041	+0.731	.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 765 associations by consensus.

Negative regulation of gene expression, epigenetic by C6orf118 expression — SOFT_TISSUE

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